<Title> Royal jelly
enhances antigen-specific mucosal IgA response
<Authors>
Kai H, Motomura Y, Saito S, Hashimoto K, Tatefuji T,
Takamune N, Misumi S
<Journal> Food
Science & Nutrition in press. (2013)
<Title> Glyceraldehyde 3-phosphate dehydrogenase
negatively regulates human immunodeficiency virus type 1 infection
<Authors>
Kishimoto N., Onitsuka A., Kido K., Takamune N., Shoji S., Misumi S.
<Journal> Retrovirology, 9, 107
(2012)
<Title> Central Nervous System
Compartmentalization of HIV-1 Subtype C Variants Early and Late in Infection in
Young Children
<Authors>
Sturdevant CB., Dow A., Jabara CB., Joseph SB., Schnell G., Takamune N.,
Mallewa M., Heyderman RS., Van Rie A., Swanstrom R.
<Journal> PLoS Pathog, 8, e1003094
(2012)
<Title>Induction of extremely low protein expression level by fusion
of C-terminal region of Nef
<Authors>Takamune
N, Irisaka Y, Yamamoto M, Harada K, Shoji S, and Misumi S
<Journal>
Biotechnol Appl Biochem.,59, 245-253 (2012)
<Title>Fluorescence imaging of potassium ions in living cells using a
fluorescent probe based on a thrombin binding aptamer-peptide conjugate.
<Authors>Ohtsuka
K, Sato S, Sato Y, Sota K, Ohzawa S, Matsuda T, Takemoto K, Takamune N,
Juskowiak B, Nagai T, Takenaka S.
<Journal>Chem.
Commun., 48, 4740-4742 (2012)
<Title>Characterization
of the hepatic cellular uptake of α(1) -acid glycoprotein (AGP), part 1: a
peptide moiety of human AGP is recognized by the hemoglobin β-chain on mouse
liver parenchymal cells.
<Authors>Nishi
K, Komori H, Kikuchi M, Uehara N, Fukunaga N, Matsumoto K, Watanabe H, Nakajou
K, Misumi S, Suenaga A, Maruyama T, Otagiri M
<Journal>J
Pharm Sci., 101 (4), 1599-606. (2012)
<Title>Effect of recipient-derived cells on the progression of
familial amyloidotic polyneuropathy after liver transplantation: a
retrospective study
<Authors>Ohya
Y, Jono H, Nakamura M, Hayashida S, Ueda M, Obayashi K, Misumi S, Asonuma K,
Ando Y, Inomata Y.
<Journal>
Ann Clin Biochem.,47, 529-534 (2010)
<Title>Suppression of human immunodeficiency virus type-1 production
by coexpression of catalytic-region-deleted N-myristoyltransferase mutants
<Authors>Takamune
N, Kuroe T, Tanada N, Shoji S, and Misumi S
<Journal>
Biological & Pharmaceutical Bulletin, 33 (12) 2018-2023 (2010)
<Title>Treatment of breast cancer cells with proteasome inhibitor
lactacystin increases the level of sensitivity to cell death induced by Human
immunodeficiency virus type 1
<Authors>
Endo M, Gejima S, Endo A, Takamune N, Shoji S, and Misumi S
<Journal>
Biological & Pharmaceutical Bulletin, 33 (11) 1903-1906 (2010)
<Title>Uncoating of human immunodeficiency virus type 1 requires
prolyl isomerase PIN1.
<Authors>Misumi
S, Inoue M, Dochi T, Kishimoto N, Hasegawa N, Takamune N, Shoji S
<Journal>J
Biol Chem. 285 (33) 25185-95. (2010)
<Title>Highly sensitive analysis of the interaction between HIV-1 Gag
and phosphoinositide derivatives based on surface plasmon resonance.
<Authors>Anraku
K, Fukuda R, Takamune N, Misumi S, Okamoto Y, Otsuka M, Fujita M.
<Journal>Biochemistry
49 (25): 5109-15 (2010)
<Title>Targeted delivery of immunogen to primate m cells with
tetragalloyl lysine dendrimer.
<Authors>Misumi
S, Masuyama M, Takamune N, Nakayama D, Mitsumata R, Matsumoto H, Urata N,
Takahashi Y, Muneoka A, Sukamoto T, Fukuzaki K, Shoji S.
<Journal>J
Immunol. ;182(10):6061-70. (2009)
<Title>Polypseudorotaxane Formation of Randomly-Pegylated Insulin
with Cyclodextrins: Slow Release and Resistance to Enzymatic Degradation
<Authors>Taishi
HIGASHI, Fumitoshi HIRAYAMA,* Shogo MISUMI, Keiichi MOTOYAMA, Hidetoshi ARIMA,
and Kaneto UEKAMA
<Journal>Chem.
Pharm. Bull. 57(5) 541—544 (2009)
<Title>Slow-release system of pegylated lysozyme utilizing formation
of polypseudorotaxanes with cyclodextrins
<Authors>Taishi
Higashi, Fumitoshi Hirayama, Shogo Yamashita, Shogo Misumi, Hidetoshi Arima,
Kaneto Uekama
<Journal>International
Journal of Pharmaceutics 374, 26–32 (2009)
<Title>Development of cell-expressed and virion-incorporated
CCR5-targeted vaccine.
<Authors>
Misumi S, Eto A, Mitsumata R, Yamada M, Takamune N, Shoji S.
<Journal>Biochem
Biophys Res Commun. 377(2):617-621 (2008)
<Title>Nonhuman primate intestinal villous M-like cells: an effective
poliovirus entry site.
<Authors>
Takahashi Y, Misumi S, Muneoka A, Masuyama M, Tokado H, Fukuzaki K, Takamune N,
Shoji S
<Journal>Biochem
Biophys Res Commun. 368(3):501-507 (2008)
<Title>HIV-1 production is specifically associated with human NMT1
long form in human NMT isozymes
<Authors>
Takamune N, Gota K, Misumi S, Tanaka K, Okinaka S, and Shoji S.
<Journal>Microbes
and Infection, 10(2) 143-150 (2008)
<Title> Design and evaluation of
polypseudorotaxanes of pegylated insulin with cyclodextrins as sustained
release system
<Authors> Higashi T, Hirayama F, Misumi S, Arima H, Uekama K.
<Journal>
Biomaterials. 28, 3866-3871 (2008)
<Title>Human immunodeficiency virus-induced apoptosis of human breast
cancer cells via CXCR4 is mediated by the viral envelope protein but does not
require CD4.
<Authors>
Endo E, Inatsu A., Hashimoto K., Takamune N, Shoji S. and Misumi S.
<Journal>Curr.
HIV Res., 6(1), 34-42 (2008)
<Title>A transgenic rat with the human ATTR V30M: a novel tool for
analyses of ATTR metabolisms
<Authors>
Ueda M, Ando Y, Hakamata Y, Nakamura M, Yamashita T, Obayashi K, Himeno S, Inoue
S, Sato Y, Kaneko T, Takamune N, Misumi S, Shoji S, Uchino M, Kobayashi E.
<Journal>Biochem
Biophys Res Commun. 2007 Jan 12;352(2):299-304.
<Title>Immunoreactive
cycloimmunogen design based on conformational epitopes derived from human
immunodeficiency virus type 1 coreceptors: cyclic dodecapeptides mimic
undecapeptidyl arches of extracellular loop-2 in chemokine receptor and inhibit
human immunodeficiency virus type 1 infection
<Authors>
Shogo Misumi, Nobutoki Takamune, and Shozo Shoji
<Journal>Endocrine,
Metabolic & Immune Disorders - Drug Targets 2007 Jun (2); 141-52. Review.
<Title>Analysis of amyloid fibrils
in the cheetah (Acinonyx jubatus).
<Authors>
Bergstrom J, Ueda M, Une Y, Sun X, Misumi S, Shoji S, Ando Y.
<Journal>Amyloid.
2006 Jun;13(2):93-8.
<Title>Lipid droplets are present
in amyloid deposits in familial amyloidotic polyneuropathy and dialysis related
amyloidosis.
<Authors>
Sun X, Ueda M, Yamashita T, Nakamura M, Bergstrom J, Zeledon Ramirez ME,
Okajima M, Misumi S, Shoji S, Motomiya Y, Ando Y.
<Journal>Amyloid.
2006 Mar;13(1):20-3.
<Title>Effects of Immunization
with CCR5-Based Cycloimmunogen on Simian/HIVSF162P3 Challenge.
<Authors>
Misumi S, Nakayama D, Kusaba M, Iiboshi T, Mukai R, Tachibana K, Nakasone T,
Umeda M, Shibata H, Endo M, Takamune N, Shoji S.
<Journal>J
Immunol. 176, 463-471 (2006)
<Title>Suppression of multiclade
R5 and X4 human immunodeficiency virus type-1 infections by a coreceptor-based
anti-HIV strategy.
<Authors>
Nakayama D, Misumi S, Mukai R, Tachibana K, Umeda M, Shibata H, Takamune N,
Shoji S.
<Journal>J
Biochem. 138, 571-582 (2005)
<Title>Zn2+ binding to
cysteine-rich domain of extracellular human Immunodeficiency virus type-1 Tat
protein is associated with Tat protein-induced apoptosis.
<Authors>
Misumi,S., Takamune,N., Ohtsubo,Y., Waniguchi,K., and Shoji,S.
<Journal>AIDS
Res. Hum. Retroviruses. 20, 297-304 (2004)
<Title>Blocking of Human
Immunodeficiency Virus Type-1 Virion Autolysis by Autologous p2gag Peptide
<Authors>
Shogo Misumi, Yukimi Morikawa, Mitsunori Tomonaga, Kouichi Ohkuma, Nobutoki
Takamune, and Shozo Shoji
<Journal>Journal
of Biochemistry. 135, 447-453 (2004)
<Title>Proteomics of HIV-1 virion
<Authors>Misumi,S.,
Takamune,N., and Shoji, S.
<Journal>BIOMEDICAL
AND PHARMACEUTICAL APPLICATIONS OF PROTEOMICS (Editor H. Hondermarck) Kluwer
Academic Publisher, The Netherland. Chapter 14, 339-366 (2004)
<Title>HIV-1粒子のプロテオーム研究
<Authors>
三隅将吾、高宗暢暁、庄司省三
<Journal>遺伝子医学 in press (2004)
<Title>A novel cyclic peptide immunization
strategy for preventing HIV-1/AIDS infection and progression.
<Authors>
Misumi S, Endo M, Mukai R, Tachibana K, Umeda M, Honda T, Takamune N, Shoji S.
<Journal>J.
Biol. Chem. 278,32335-32343 (2003)
<Title>HIV-1感染および病態進行を阻止する新規環状ぺプチドワクチンの開発に向かって -HIV-1コレセプターに対する自己抗体誘導によるHIV-1感染阻害-
<Authors>三隅将吾、高宗暢暁、庄司省三
<Journal>医学のあゆみ 207, 67-72. (2003)
<Title>Three isoforms of cyclophilin A
associated with human immunodeficiency virus type 1 were found by proteomics
using two-dimensional gel electrophoresis and matrix-assisted laser desorption/ionization-time-of-flight
mass spectrometry
<Authors>
Shogo Misumi, Takashi Fuchigami, Nobutoki Takamune, Ichiro Takahashi, Michiho
Takama, and Shozo Shoji
<Journal>J.
Virol. 76,10000-10008. (2002)
<Title>Development of enzyme-linked
immunosorbent assay for measurement of activity of myristoyl Coenzyme A:
protein N-myristoyltransferase
<Authors>
Nobutoki Takamune, Hirotoshi Hamada, Hideki Sugawara, Shogo Misumi, and Shozo
Shoji
<Journal>Anal.
Biochem. 309,137-142 (2002)
<Title>Novel strategy for anti-HIV-1 action:
selective cytotoxic effect of N-myristoyltransferase inhibitor on
HIV-1-infected cells.
<Authors>
Nobutoki Takamune, Hirotoshi Hamada, Shogo Misumi, and Shozo Shoji
<Journal>FEBS
Lett.527,138-142(2002)
<Title>A
novel localized amyloidosis associated with lactoferrin in the cornea
<Authors> Ando Y, Nakamura M, Kai H, Katsuragi S, Terazaki H, Nozawa
T, Okuda T, Misumi S, Matsunaga N, Hata K, Tajiri T, Shoji S, Yamashita T,
Haraoka K, Obayashi K, Matsumoto K, Ando M, Uchino M.
<Journal>Lab
Invest. 82, 757-766 (2002)
<Title>Acid-labile formylation of amino
terminal proline of human immunodeficiency virus type 1 p24gag was found by
proteomics using two-dimensional gel electrophoresis and matrix-assisted laser
desorption/ionization-time-of flight mass spectrometry
<Authors>
Takashi Fuchigami, Shogo Misumi, Nobutoki Takamune, Ichiro Takahashi, Michiho
Takama, and Shozo Shoji
<Journal>Biochem.
Biophys. Res. Commun. 293, 1107-1113 (2002)
<Title>HIV-1粒子のプロテオーム解析
<Authors>庄司省三、三隅将吾
<Journal>日本臨床60巻4号、636-640 (2002)
<Title>Presence of autoantibody against ATTR
Val30Met after sequential liver transplantation.
<Authors>
Ando Y, Terazaki H, Haraoka K, Tajiri T, Nakamura M, Obayashi K,Misumi S, Shoji
S, Hata K, Nakagawa K, Ishizaki T, Uemoto S, Inomata Y, Tanaka K, Okabe H.
<Journal>Transplantation,
73, 751-755 (2002).
<Title>Presence of variant transthyretin in
aqueous humor of a patient with familial amyloidotic polyneuropathy after liver
transplantation.
<Authors>
6) Haraoka, K., Ando, Y., Ando, E., Sun, X., Nakamura, M., Terazaki, H.,
Misumi, S., Tanoue, Y., Tajiri, T., Shoji, S., Ishizaki, T., Okabe, H., and
Tanihara, H.
<Journal>Amyloid,
9, 247-251 (2002).
<Title>Down-regulation of N-myristoyl
transferase expression in human T-cell line CEM by human immunodeficiency virus
type-1 infection.
<Authors>Nobutoki
Takamune, Tadahiro Tanaka, Hiroki Takeuchi, Shogo Misumi, and Shozo Shoji
<Journal>FEBS
Letters 506, 81-84, (2001).
<Title>A cyclic
dodecapeptide-multiple-antigen-peptide-conjugate from undecapeptidyl arch (from
Arg168 to Cys178) of extracellular loop2 in CCR5 as a novel HIV-1 vaccine.
<Authors>Shogo
Misumi, Reina Nakajima, Nobuoki Takamune, and Shozo Shoji,
<Journal>J.
Virol. 75, 11614-11620 (2001).
<Title>Variant transthyretin in blood
circulation can transverse the blood-cerebrospinal barrier: qualitative
analyses of transthyretin metabolism in sequential liver transplantaion.
<Authors>
Hisayasu Terazaki, Yukio Ando, Masaaki Nakamura, Konen Obayashi, Shogo Misumi,
Shozo Shoji, Sonoka Yamashita, Kazuko Nakagawa, Takashi Ishizaki, Ole Suhr,
Shinji Uemoto, Yukihiro Inomata, and Koichi Tanaka.
<Journal>Transplantation,
72, 296-299 (2001).
<Title>Evidence
as a HIV-1 self-defense vaccine of cyclic chimeric dodecapeptide warped from
undecapeptidyl arch of exracellular loop 2 in both CCR5 and CXCR4.
<Authors>Shogo
Misumi, Nobuoki Takamune, Yasuhide Ido, Shinichiro Hayashi, Masafumi Endo,
Ryouzaburou Mukai, Kuniomi Tachibana, Mamoru Umeda, and Shozo Shoji
<Journal>Biochem.
Biophys. Res. Commun. 285(5), 1309-1316 (2001)
<Title>
Myristoylation of Human Immunodeficiency Virus Type 1 gag Protein Is Required
for Efficient env Protein Transportation to the Surface of Cells.
<Authors>
Shiraishi T, Misumi S, Takama M, Takahashi I, and Shoji S.
<Journal>
Biochem. Biophys. Res. Commun. 282, 1201-1205 (2001)
<Title>
Cyclic Zinc-Dithiocarbamate-S,S'-Dioxide Blocks CXCR4-mediated HIV-1 Infection.
<Authors>
Nobutoki Takamune, Shogo Misumi, and Shozo Shoji
<Journal>
Biochem. Biophys. Res. Commun. 272, 351-356 (2000)
<Title>
A novel compound heterozygote (FAP ATTR Arg104His/ATTR Val30Met) with high
serum transthyretin (TTR) and retinol binding protein (RBP) levels.
<Authors>
Terazaki H, Ando Y, Misumi S, Nakamura M, Ando E, Matsunaga N, Shoji S, Okuyama
M, Ideta H, Nakagawa K, Ishizaki T, Ando M, and Saraiva MJ
<Journal>
Biochem Biophys Res Commun, 264(2), 365-70 (1999).
<Title>
Blockage of HIV-1 production through inhibition of proviral DNA synthesis by
N,O-didecanoyl serinal dimethylacetal.
<Authors>
Nobutoki Takamune, Shogo Misumi, Kazuchika Furuishi, and Shozo Shoji
<Journal>
IUBMB Life, 48, 311-315 (1999)
<Title>
難薬剤耐性抗HIV剤の開発，Developement of anti-HIV-1 drug for
drug-resistant HIV-1.
<Authors>
庄司 省三
<Journal>
最新医学 第53巻2047-2060(1998).
<Title>
タンパク質のN-ミリストイル�ｻの生物学的意義 −とくにHIV-1 gagタンパク質のN-ミリストイル化の役割−，Role of protein
N-myristoylation in HIV-1 gag protein.
<Authors>
庄司 省三
<Journal>
生化学，70, 222-226 (1998).
<Title>
An allosteric drug, o,o'-bismyristoyl thiamine disulfide suppresses HIV-1
replication through prevention of nuclear translocation of both HIV-1 Tat and
NF-kB.
<Authors>
Shozo Shoji, Kazuchika Furuishi, Akihito Ogata, Kazunobu Yamataka, Kuniomi
Tachibana, Ryozaburo Mukai, Akihiko Uda, Kazunobu Harano, Shuzo Matsushita, and
Shogo Misumi
<Journal>
Biochem. Biophys. Res. Commun., 249(3), 745-53 (1998).
<Title>
The p2gag peptide, AEAMSQVTNTATIM, produced from HIV-1 Pr55 gag was found to be
a suicide inhibitor of HIV-1 protease.
<Authors>
Shogo Misumi, Akiko Kudo, Ryuji Azuma, Mitsunori Tomonaga, Kazuchika Furuishi,
and Shozo Shoji
<Journal>
Biochem. Biophys. Res. Commun., 241, 275-280 (1997).
<Title>
Blockage of N-myristoylation of HIV-1 gag induces the production of impotent
progeny virus.
<Authors>
Kazuchika Furuishi, Hidekazu Matsuoka, Michiho Takama, Ichiro Takahashi, Shogo
Misumi, and Shozo Shoji
<Journal>
Biochem. Biophys. Res. Commun., 237, 504-511 (1997).
出願番号
発明の名称
特許論文
特願2002-325506
ペプチド及びその利用
J. Biol. Chem. 278,32335-32343 (2003)
特願2002−230699
抗HIV剤、エイズ予防治療剤
特願2002-212406
N-ミリストイルトランスフェラーゼの性能の評価方法及び評価するためのキット
Anal. Biochem. 309,137-142 (2002)
環状ペプチド
WO99JP5973
J. Virol. 75, 11614-11620 (2001)
環状ペプチド
WO99JP6174
Biochem. Biophys. Res. Commun. 285, 1309-1316 (2001)
WO98JP2059
HIV-1プロテアーゼ阻害剤
Biochem. Biophys. Res. Commun. (1997) 241, 275-280
WO96JP3341
チアミンジスルフィド類及びこれを有効成分とする医薬
Biochem. Biophys. Res. Commun. (1998) 249, 745-753.
WO95JP85
抗HIV剤
Biochem. Biophys. Res. Commun.(1994)20, 967-975
WO93JP981
抗HIV剤
Biochem. Biophys. Res. Commun.(1993)194, 610-621
平9-139372
HIV-1プロテアーゼ阻害剤
Biochem. Biophys. Res. Commun. (1997) 241, 275-280
平9-256071
抗NMTモノクローナル抗体、ハイブリドーマ及びNMTを検出する方法
平7-147259
チアミンジスルフィド類
Biochem. Biophys. Res. Commun. (1998) 249, 745-753
平6-173042
抗HIV剤
Biochem. Biophys. Res. Commun.(1994)20, 967-975.
平6-7160
抗HIV剤
Biochem. Biophys. Res. Commun.(1993)194, 610-621
平4-34439
抗HIV剤
IUBMB Life, 48: 1-5 (1999)
平4-201209
抗HIV剤
IUBMB Life, 48: 1-5 (1999)
韓国227095
抗HIV剤
Biochem. Biophys. Res. Commun. (1998) 249, 745-753
米国5886000
ANTI-HIV AGENT
Biochem. Biophys. Res. Commun. (1998) 249, 745-753
特許2725772
ミリストイル化合物である、ウイルス構成蛋白のミリストイル化抑制剤
J. Biochem. (1988) 103, 747-749.
特許2627896
ミリストイル化合物、その調製法及び用途
特許2524505
ミリストイルグリシン部位を識別する抗体
Biochem. Biophys. Res. Commun. (1996)222, 344-351